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1.All proteases use water to cut their respective proteins, and enzymes in the aspartyl protease family employ a pair of aspartic acids to activate a water molecule for this purpose.
所有的蛋白酶都会利用水来切割其作用的蛋白质，而天冬胺酸蛋白酶家族的成员，则还会利用两个天冬胺酸分子来活化水分子，以利蛋白质的切割。收藏指正
2.Sequence analysis and alignment showed significant homologies with the correlated parasite cysteine proteinases, and the Cys, His and Asn residues that formed catalytic triad were of high conservation.
氨基酸序列的同源性分析显示 ,该序列与相关虫种半胱氨酸蛋白酶存在着很高的同源性 ,组成半胱氨酸催化三联体的半胱氨酸、组胺酸和天冬酰胺残基高度保守。收藏指正
3.Sequence analysis and alignment showed significant homologies with the correlated parasite cysteine proteinases and conservation of Cys,His and Asn residues that form a catalytic triad.
将推导的氨基酸序列作同源性分析显示 ,该序列与相关虫种半胱氨酸蛋白酶存在着较高的同源性 ,组成半胱氨酸催化三联体的半胱氨酸、组胺酸和天冬酰胺残基高度保守。收藏指正
4.Members of this subset—which includes the protease involved in replicating HIV, the virus that causes AIDS—use aspartic acid, a type of amino acid, to catalyze the protein-cutting reaction.
这群蛋白酶会利用天冬胺酸这种胺基酸来催化蛋白切割反应，其成员包括参与爱滋病毒HIV复制的蛋白酶。收藏指正
5.The deduced 410 amino acid of CTSD was predicted to contain an Asn(Asparagine) domain which was the representative structure of lysosomal aspartic proteinase by blast in NCBI,and three-dimentional structure of porcine CTSD showed 99.7% alignment to that of mammalian CTSD.
在NCBI进行Blast P搜索结果显示猪CTSD氨基酸结构中含有Asn(Asparagine,天门冬酰胺)结构域,与天冬氨酸蛋白酶3D结构同源性高达99.7%,具有真核生物天冬氨酸蛋白酶的典型结构。收藏指正
6.Sequence analysis and alignment showed significant homologies with the correlated parasite cysteine proteases and conservation of Cys,His and Asn residues that form a catalytic triad.
氨基酸序列的同源性分析显示 ,该序列与相关虫种半胱氨酸蛋白酶存在着很高的同源性 ,组成半胱氨酸催化三联体的半胱氨酸、组氨酸和天冬酰胺残基高度保守。收藏指正
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