早已认识的
1.It may describe a person who has been known for a long time but is not necessarily old in years.
2."For she and I were long acquainted/And I knew all her ways"(A.E. Housman).
3.The existence of Endogenous Opioid Peptide (EOP) has been known for a long time, and it has been recognized that EOP has a central paregoric effect and can regulate cardiovascular functions.

