羟苯磺酸钙
1.Calcium dolesilate has been shown to significantly reduce platelet adhesiveness, inhibit platelet aggregation, reduce plasma and serum viscosity in rabbits.
2.[Methods]Rats were induced to Diabetic model by unilateral nephrectomy and intraperitoneal injection 1%STZ(55mg/kg), each group administrated Calcium dobesilate or distilled water respectively. Twelve weeks later, the change of the ultrastructure of kidneys and change of BG、Upro、Cc 、BUN and Kidney/body weight rate were observed in each group.
3.[Results]After 12 weeks, BG、Upro、Cc 、BUN and Kidney/body weight rate in Group DM rats increased and obviously higher than those of Group NC, but decreased statistically compared to those of Group DD.
