CML-BC
1.No FLT3 -TDK mutation was found in 25 ALL, 2 AHL,17 MDS and 7 CML-BC patients.
2.Methods Real-time quantitative retroverse polymerase chain reaction (QRT-PCR) method was used for detecting RbAp46 expression levels in BM cells of 140 patients with acute leukemia (AL),13 with chronic myelogenous leukemia in chronic phase (CML-CP), 7 with CML in blast crisis (CML-BC) and 32 with non-leukemic disorders.
3.Results One case achieved progress and another obtained remission in relapsed MM, respectively, 5 CR1 and 1 PR2 and 1 NR in 7 APL, 2 CR and 2 PR and 1 NR in 5 CML BC cases, 1 CR and 1 NR in 2 MDS.
4.1. Immunophenotypic analysis was performed using a panel of monoclonal antibodies and three/four-color immunofluorescence staining methods of flow cytometry in patients with CML in BC.
5.12 chronic myeloid leukemia (CML) (CP 5,AP 2, BC 4 and relapse after allo BMT 1);
6.Methods : We have chosen 37 CML cases, including 27 chronic phase (CP), 5 accelerated phase (AP) and 5 blast crisis (BC) cases .

