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1.An animal model of fulminant hepatic failure induced by thioacetamide wasused and Evans blue extracted from brain tissue was taken as the index of blood-brainbarrier permeability.
采用硫代乙酰胺所致大鼠暴发性肝衰模型,以脑组织浸泡液中Evans蓝含量为血脑屏障通透性指标。收藏指正
2.lung permeability index,content of evans blue and pathomorphological score in group S1L decreased from 4 86±0 82,112 21±11 44 ng/mg,9 17±0 90 to 3 98±0 50,92 85±11 80 ng/mg,7 50±0 96;
结果 七氟醚1L组肺通透指数、伊万斯蓝含量、病理形态学积分分别由 4 6 8± 0 82 ,( 112 2 1± 11 4 4 )ng/mg ,9 17± 0 90下降到 3 98± 0 5 0 ,( 92 85± 11 80 )ng/mg ,7 5 0± 0 96 ;收藏指正
3.Results:In comparison with poisoning group (group B, n =20) the surival rate (80%) in group E was the highest meanwhile the pulmonary index and cotent of Evans blue in group E were significantly decreased ( P <0 05 or P <0 01).
结果 :与实验中毒 (B组 ,n=2 0 )对比 ,存活率以 E组最高 (80 % ) ,肺系数及伊文思蓝含量也以 E组显著降低 (P<0 .0 5或 P<0 .0 1)。收藏指正
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