LOD score
3.Results: The results produced by MLINK program are as follows: In three pedigrees including HY-01, CY-01 and CY-02, the maximum sum two-point LOD score of 2.151 for D16S3131 was obtained at recombination rates of 0.000 under autosomal dominant model with 90% penetrance.
4.The LOD score was 2.689.45.Three QTLs qGL-5,qGWt-1a and qGWt-1b were both detected under upland and lowland environments(common QTL). Two co-localized QTLs(qGL-1a and qGWt-1a,and qGL-1b and qGWt-1b) controlling GL and GW were detected.
5.2. All affected individuals displayed bilateral lens opacities, and pulverulentcataract cataract with variable severity. 3. The LOD score of each selected markers ADCC in FANS family was negative. 4. An abnormal band was found by SSCP in a patient, and sequence analysis proved a deletion of CA in none coding region of GJA3 gene.
