abundance of the heart
8.Sarcoplasmic reticulum Ca~(2+)-ATPase (SERCA) and SERCA regulatory protein phospholamban (PLB) are the major proteins responsible for intracellular Ca~(2+) homeostasis throughout excitation-contraction cycling in cardiomyocytes. Changes in the abundance and/or function of these molecules in heart failure have been variable in previous studies.

