5.The angiopoietin (Ang) family is important angiogenesis factor, including four members: Ang-1, Ang-2, Ang-3, Ang-4 It play critical role for blood vessel formation.
7.Methods Neonatal rat cultured cardiac fibroblasts were randomly divided into 5 groups: control, Ang Ⅱ, Ang(1-7) , Ang Ⅱ+Ang(1-7) , and Ang Ⅱ+Ang(1-7) +HOE-140. Fibroblasts proliferation was assessed by thymidine incorporation.