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1.Objective To investigate if an adenovirus vector carrying antisence multidrug resistance gene 1 (MDR1) could reverse multidrug resistance (MDR) of HepG2/ adriamycin (ADM) cells in tumors transplanted in athymic mice. Methods An adenovirus vector carrying AFP promoter and antisence MDR1 was constructed.
目的探讨携带多药耐药基因1(multidrug resistance gene 1,MDR1)反义RNA重组腺病毒载体在裸鼠体内逆转肝癌多药耐药细胞HepG2／阿霉素(adriamycin,ADM)的疗效及作用机制。收藏指正
2.Photodynamic therapy for human gastric cancer using 5-aminolaevulinic acid-induced protoporphyrin IX:an in-vivo study in athymic nude mice
5-氨基乙酰丙酸光动力治疗裸小鼠胃移植癌的实验研究收藏指正
3.METHODS⑴ A total of 20 athymic nude mice were used to establish human adriamycin-resistant HepG/ADM model. They were randomized to two groups: HepG2 group, in which 10 nude mice received a subcutaneous injection of 5 x 106/ml adriamycin-sensitive HepG2 cells;
方法⑴ 20只裸鼠建立阿霉素耐药株HepG2/ADM动物模型，它们被随机分成两组：HepG2组：10只裸鼠接受皮下注射5×106/ml阿霉素敏感的HepG2细胞；收藏指正
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