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1.THE 57TH AMINO ACID OF HLA-DQ BETA CHAIN AND THE IDDM SUSCEPTIBILITY IN SHANGHAI HANS
HLA-DQβ链57位氨基酸与上海地区汉族IDDM易感性收藏指正
2.Three days after spinal cord injury,there were 13 up-regulated proteins such as macrophage migration inhibitory factor(MIF),heat-shock protein 27(HSP27),syndecan-3(SDC3),T-cell receptor beta chain precursor V region(CRTB4),annexin Ⅲ(ANXⅢ),galectin-3(LEG3),pyruvate dehydrogenase(ODPA),chromogranin A precursor(CgA),HSP70-binding protein 1(HSPBP1).
脊髓损伤3d后表达上调的蛋白质有巨噬细胞游走抑制因子、S期激酶相关蛋白1、热休克蛋白27、多配体蛋白聚糖3、T细胞受体β链可变区、膜联蛋白Ⅲ、腺苷酸激酶1、半乳凝素3、丙酮酸脱氢酶、磷脂酶B、嗜铬粒蛋白A、热休克蛋白70凝结蛋白1;收藏指正
3.Objective To analyze the drift of the complementarity-determining region 3 (CDR3) of T cell receptor beta (TCRβ) chain variable region in T cells of healthy volunteers cultured with interleukin-2 (IL-2).
目的研究IL-2对体外培养的T细胞TCRβ链CDR3谱系漂移的影响。收藏指正
4.The results were as followed: (1) In all periods, the expression of cholesterol side chain decomposition enzyme (P450scc) , 3 beta-hydroxysteroid dehydrogenase(3β-HSD),steroidogenic acute regulatory protein (StAR) mRNA and protein had no significant change.
结果显示:(1)在不同年龄阶段,P450scc(胆固醇支链裂解酶)mRNA、3β-HSD(3β-羟胆固醇脱氢酶)mRNA、StAR(类固醇合成快速调节蛋白)mRNA和蛋白的水平无明显变化;收藏指正
5.2) Clinical isolates with reduced susceptibility to Imipenem and/or Ceftazidime were subjected to PCR (Polymerase Chain Reaction) analyses with primers specifically target to bla_(VIM) and bla_(IMP) genes for detecting metallo-beta-lactamase genes maybe harbored.
2)针对金属β-内酰胺酶基因bla_(VIM)和bla_(IMP)设计引物,采用聚合酶链反应(PCR)技术检测金属β-内酰胺酶的存在情况;收藏指正
6.differential screening and homology analysis identified 6 differentially expressed genes associated with cytoskeletal remodeling, including slingshot 2L(SSH-2L), PP1 catalytic subunit, beta isoform(PP1Cβ), dedicator of cytokinesis 8(DOCK-8), Homo sapiens protein tyrosine phosphatase non-receptor type 6 and 12(PTPN6, PTPN12), myosin regulatory light chain interacting protein(MIR).
结果:构建了高效的上调与下调消减cDNA文库,经鉴定及同源性分析有6个与细胞骨架重建有关,包括上调基因slingshot磷酸酶(SSH-2L),蛋白磷酸酶1β亚型(PP1Cβ),无功能糖基转移酶样蛋白(DOCK-8),蛋白酪氨酸磷酸酶非受体型6(PTPN6)与非受体型12(PTPN12);收藏指正
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