• 基本释义

1.Distinct COX-2 expression of IRESSA combinated chemotherapeutics with different successions on GLC-82
IRESSA联合化疗药物不同次序对肺癌细胞系GLC-82 COX-2表达的影响收藏指正
2.And when we achieve the saturated concentration of chemotherapeutics, MPA dose not continue to raise inhibition ratio.
并且化疗药已达到饱和浓度时甲孕酮不能继续提高抑制率。收藏指正
3.Experiment group are divided into MPA group, chemotherapeutics group and combine group we select Gamzar as chemotherapeutics, put cell into different factors, after several hours detect apoptosis rate ,observe morphologic change of apoptosis cell.
试验组分为空白组,甲孕酮组,化疗药物组和联用甲孕酮组(5umol/L和10umol/L),其中化疗药物选择健泽(30umol/L),经过与化疗药物4小时、6小时和8小时作用以后,用TUNEL法检测细胞凋亡率,观察凋亡细胞的形态学变化。收藏指正
4.Methods:Experimental cell are divided into blank group (culture), control group (cell) and experiment group (cell + different factors). Experiment groups are divided into MPA group, chemotherapeutics group and combine group to contrast.
方法:实验细胞分成空白组(培养基)、对照组(单细胞悬液)和实验组(单细胞悬液经过各种处理因素),实验组又分甲孕酮组、单用化疗药物组和联合甲孕酮(5umol/L和10umol/L)组进行对比。收藏指正
5.Result:1. the growth inhibiting of A549 with Gemzar+MPA (5umol/L) are much better than the one of haplo- chemotherapeutics group, it has statistical significance p<0.01.it can not improve the inhibition ratio of tumor cell by Adding dose.
1.健泽与甲孕酮(5umol/L)联合应用时对A549细胞生长抑制作用较单用健泽时有明显的提高,具有统计学意义P<0.01。 加大甲孕酮的计量时未能继续提高对肿瘤细胞的抑制率。收藏指正
6.Methods:239 patients after performing an operation with esophageal carinoma were investigated,12 risk factors (ordinary condition of patients,chemotherapeutics and actinotheraphy before operation,processing operation,body temperature after operation,etc.) were studied. With SAS the single factor analysis was processed.
方法:对239 例接受手术治疗的食管癌患者的一般情况,术前接受化疗和放疗、术中情况、术后体温、切口愈合情况等12 个因素进行回顾性调查,并将诸因素分为宿主、手术及诊疗因素3 部分,采用SAS软件进行单因素分析。收藏指正
7.MPA is chiefly administrated in the treatment of gynecological tumor. The purpose of the experiment is to investigate the effect of MPA combination chemotherapy in A549 by MPA+ two chemotherapeutics (Carboplatin or Gemzar) and investigate if chemotherapy combination chemotherapy with MPA can promote the effect of synergism in A549 and accelerate the course of apoptosis and provide experimental proof for clinical application.
本实验通过甲孕酮(MPA)分别与两化疗药物(卡铂和健泽)联合应用后对肺腺癌细胞珠(A549)的作用,探讨甲孕酮联合化疗是否对A549细胞株具有协同杀伤作用并促进凋亡的进程,为临床联合应用提供实验依据。收藏指正
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