chromosome abnormality
7.Hyperdiploid chromosome abnormality was seen in 5(5/14) untreated patients with psoriasis and significantly higher than normal.
9.ObjectiveA deletion of the long arm of chromosome 20 (del(20q) or 20q-) is the most frequent cytogenetic finding in malignant hematologic diseases with abnormalities of chromosome 20. In malignant hematologic diseases with a solitary chromosomal abnormality, 20q-represents the second most common structural abnormality after the Philadelphia chromosome.
10.It was found that rhGM-CSF oral drug showed no genotoxicity either in vitro or in vivo through the micronu-cleus test,CHL chromosome aberration test and Ames test. No abnormality was found in general reproductivetoxicity test,and toxicity test in perinatal stage and sensitive period to teratogenic agent,which suggests littlereproductive toxicity.
