concentration curve
1.Results:A linearity of ACS concentration curve was within 2～2?048?μg·L-1.The minimal detection limit was 2.0?μg·L-1.The retention time of ACS was 2.4?min.
2.Results 5-HT concentration-response curve demonstrated that absorbance peak occurred at 1 μmol/L without further increment with higher concentration.
3.These parameters influence the maximum （peak） concentration, the time at which the maximum concentration occurs （peak time）, and the area under the concentration-time curve （AUC） after a single oral dose.
4.Results Bre shifted the concentration-response curve for NA to right in a dose-dependent manner , but shifted that for high potassium to left;
5.Mean area under the plasma concentration-time curve from zero to infinity (AUC_(0-∞)) was (47±49) μg·h·L~(-1) for LOR and (181±122) μg·h·L~(-1) for DCL, respectively.
7.A TAA concentration peak protruded in the curve right after injection of ascorbic acid,accompanied by dramatic reduction of DHAA/TAA.
8.METHODS:The antibacterial activity of MLN/TAZ (1 : 0,2 : 1,4: 1) were tested by the method of minimal inhibitory concentration (MIC),minimal bactericidal concentration (MBC) and time-kill curve in vitro.
9.ResultsIn the berneol group, the mean drug concentration in CSF and area under curve increased significantly ( P<0.05) compared with those of the control group, and the time of drug reaching the peak concentration in CSF was 6 hours, the ratio of CSF to plasma also increased significantly ( P<0.05), while the blood concentration not increased.
