despondence
1.HIV/AIDS despondence is emerged as a urgent and challengeable issue in the world.
2.Despite my despondence triggered by her disregard, I kept up with my endeavor.
3.Psychological questions such as: sensitive interpersonal relationship, anxious psychology, despondence, introversion, instability, self-abasement, and overweight psychological burden are universal existence in impoverished college students.
