• 基本释义

1.EPR Study of Cu(Ⅱ )-dipeptide Complexes
Cu(Ⅱ)-二肽络合物的EPR研究收藏指正
2.Common dipeptide were CC、CF、MH、CQ、CK、CH、HC、HN、WC、CY、AC、KC、GC、CP、LC、QT、FC、WH、QC and RR. In rich characteristic dipeptide,the high optimal pH alpha-amylase had the greatest significance.
共性二肽为CC、CF、MH、CQ、CK、CH、HC、HN、WC、CY、AC、KC、GC、CP、LC、QT、FC、WH、QC和RR;收藏指正
3.The Boc protected phenylalanine (Boc-Phe-OH) reacted with phenylalanine amide to give the first dipeptide Boc-Phe-Phe-NH_2 in 86% yield.
以叔丁氧羰酰基(Boc)作为苯丙氨酸的氨基保护基,先制备苯丙氨酸酰胺三氟乙酸盐,再用叔丁氧羰酰基(Boc)保护的苯丙氨酸与其缩合得二肽片段Boc-Phe-Phe-NH_2,产率86%。收藏指正
4.Muramyl dipeptide (MDP) and its analogues: MDP[γ- Abu]1 and MDP-Oxalys were synthesized via an improved procedure using a novel coupling reagent with high yield.
本文报道胞壁酰二肽(MDP)及其类似物MDP[γ-Abu]~1, MDP-Oxalys的合成. 应用一些新的合成方法和一种新型高效缩合剂,简化了合成步骤,提高了收率.收藏指正
5.The immunizing effect produced in mice by influenza virus surfaceanti-gen HA subunit with muramyl dipeptide ( MDP) adjuvant is identical to that of HA subunit with A1 ( OH )3 and Freund adjuvant.
流感病毒表面抗原——血凝素(HA)亚单位,在人工合成的胞壁酰二肽(MDP)佐剂配合下,注射小白鼠所产生的免疫效果与常用的Al(OH)_3及福氏佐剂相似。收藏指正
6.Gly-Asp(OBzl) 2 dipeptide was synthesized by DCC method,then Boc-Arg(NO 2 )-Gly-Asp(OBzl) 2 was synthesized by the method of mixed anhydrides.
采用二环己基碳二亚胺法(DCC)合成了二肽Gly Asp(OBzl) 2 ,然后利用混合酸酐法得到全保护RGD三肽:Boc Arg(NO2 ) Gly Asp(OBzl) 2 三肽;收藏指正
7.L-Pro-OMe·HCl from L-Pro through esterification was coupled with N-Boc-Me-D-Phe via PyAOP activation to yield dipeptide N-Boc-Me-D-Phe-Pro-OMe.
二肽用HBr/HOAc脱Cbz保护后,用BOP-Cl与Cbz保护氨基的甘氨酸偶合得到三肽N-Cbz-Gly-N-Me-D-Phe-Pro-OMe,总收率46%。 异亮氨酸的C端用叔丁酯保护。收藏指正
8.The Boc and Bzl protected tyrosine (Boc-Tyr(Bzl)-OH) was allowed to react with proline methyl ester hydrochloride to form the second dipeptide Boc-Tyr(Bzl)-Pro-OMe in 42% yield.
选择叔丁氧羰酰基(Boc)和苄基(Bzl)作为酪氨酸的氨基和侧链保护基,与脯氨酸甲酯盐酸盐缩合得二肽片段Boc-Tyr(Bzl)-Pro-OMe,产率42%。收藏指正
9.After methyl esterification and protection with(Boc)_2O,the derivate of L-serine was treated with 2,2-dimethoxypropane,followed by saponification to afford Garner acid Ⅸ. Then Ⅸ was coupled with L-threonine methyl ester to give dipeptide Ⅺ.
L-丝胺酸经甲酯化,叔丁氧羰基保护氨基后,以2,2-二甲氧基丙烷进行羟基和氨基的双保护,脱甲酯得到Garner酸,再与甲酯保护的L-苏氨酸缩合得到二肽收藏指正
10.In this paper, B3LYP/6-311G(d,p) method was applied to study the conformation stabilities of dipeptide molecule CH_3CONHCH_3. Conformation analysis was carried out from the point of view of intramolecule hydrogen bond interaction, steric interaction, and Coulomb interactions.
使用B3LYP/6 311G(d,p)方法对二肽分子CH3CO[NHCH2CO]NHCH3的所有可能稳定构象进行了研究,分析了二肽分子CH3CO[NHCH2CO]NHCH3的不同稳定构象的相对稳定性,从分子内氢键作用、大基团间的空间位阻以及库仑作用角度探讨了影响二肽构象稳定性的因素.收藏指正
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