dose fractionation
1.The effects of dose fractionation on the survival rate, the numbers ofbone marrow cells (BMC) and hemopoietic stem cells (CFU-S) per femur, and the self-renewal capacity of the CPU-S in ICR/JCL and LACA mice were investigated.
2.3) Continuous accelerated fractionation radiotherapy (CAF) received 1. 5Gy B.i. d to a total dose of 68.4Gy±44Fx/ 29～30D .
3.Patients i n the LCAF group received conventional fractionation radiotherapy of 1.8 ? Gy per fr action to a dose of 41.4? Gy/23 f/4.6 wks , followed by accelerated fraction ation irradiation using reduced fields, twice daily at 1.5?
4.Increasing local control and sur-vival after definite chemoradiation seems possible not only by using optimized radiation fractionation schedules and escalated total doses, but also by associating more convenient and less toxic chemotherapy agents at the right cytotoxic or radio-sensitizing dose.
