down-regulated
1.Identification of an EST down-regulated in nasopharyngeal carcinoma at chromosome 3p14.2
2.4. Fas mRNA was up-regulutedand Bcl-2 mRNA was down-regulated by YWN.
3.(2)There were 420 up-regulated genes and 552 down-regulated genes among 2-fold DEGs,including DKK1(dickkopf homolog 1)which was 5- fold up-regulated;
4.The effects can be traced to the down-regulated expression of Bcl-2 protein and up-regulated expression of Caspase3 protein.
5.CHM significantly down-regulated the concentration of TNF-a ( P < 0.05) and up-regulated the concentration of interleukin-2 (P<0.01).
6.(2) There were 420 up-regulated genes and 552 down-regulated genes in 2-fold DEGs, including 23 genes related to cytochrome P450;
7.Results The results of RFDD-PCR revealed down-regulated expression of eNOS and nNOS and up-regulated iNOS expression in diabetic rat retina.
8.Compared to COC_1. 143 genes were differentially expressed significantly in COC_1/DDP cells, among which 12 ribosomal protein genes were down-regulated significantly, many anti-apoptotic genes were up-regulated and apoptotic gene CASP2 was down-regulated.
9.⑵There were 420 up-regulated genes and 552 down-regulated genes in 2-fold DEGs, including 3 genes related to matrix metalloproteinases (MMPs);
10.It was found that wtFAK and FAKY576F up-regulated GalT gene expression and its surface activity, while dominant negative mutant FAKY397F down-regulated them.
