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1.The qualitative and quantitative analytical procedures used to characterize a reference standard are expected to be different from, and more extensive than, those used to control the identity, strength, quality, purity, and potency of the drug substance or the drug product.
用于界定标准品的定性和定量分析方法应当要不同于用于控制原料药或制剂的结构,剂量,质量,纯度和效力的分析方法,要比它们更深入。收藏指正
2.Quantitative description:the name and quantity of the drug substance and of each excipient in the finished product should be expressed both as amount per dosage unit and as amount per batch.
定量描述:药品中所含半制品与赋型剂之名称与含量应以单位剂量与单位批示量来表示。收藏指正
3.A drug or other substance not containing a steroid.
非类固醇物质不含类固醇的药物或者其它物质收藏指正
4.The time required for half the quantity of a drug or other substance deposited in a living organism to be metabolized or eliminated by normal biological processes.
生物半衰期存储在活的有机体内的药物或其它物质经新陈代谢或被正常的生理活动消失一半所需要的时间收藏指正
5.A drug, nutrient solution, or other substance administered into a vein.
静脉注射物注入静脉的药物、营养液、或其它物质收藏指正
6.A condition of deep stupor or unconsciousness produced by a drug or other chemical substance.
麻醉由麻醉剂或其它化学药品引起的深度昏迷或无意识状态收藏指正
7.A drug, medicinal preparation, or similar substance obtained from a plant or plants.
植物制剂取自植物的药品、药物制剂或类似物收藏指正
8.A triturated substance, especially a powdered drug.
研碎物研成粉末的物质,尤指粉末状的药收藏指正
9.hypersensitivity reaction to the ingestion or injection of a substance (a protein or drug) resulting from prior contact with a substance.
对咽下或注射到体内的物质有过敏反应。收藏指正
10.Abstract: In this paper interactions of bilayer lipid membrane with clotrimazole as the antifungal agent were reported in order to interpret the action basis about the molecularbiology of this drug.Using the injecting method, we prepared three bilayer lipid membranes(BLM) respectively,and by the cyclic voltammetry method we determined properties of BLM before and after adding clotrimazole into the membranes.It was found that clotrimazole could remarkably reduce the membrane resistance and demonstrated that the drug as an antifungal substance might certainly change the permeability of bilayer lipid membrane.
文摘:报道了抗真菌药克霉唑与人工脂膜的相互作用,试图阐明该药的分子生物学的作用基础.用注射方法分别制备3种双分子层脂膜(BLM),并运用循环伏安法测量了修饰物克霉唑加入前后人工双分子层脂膜的电性质.结果发现克霉唑可显著降低膜电阻并证实该药确能改变人工双分子层脂膜的通透性.收藏指正
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