drug substance
10.Abstract: In this paper interactions of bilayer lipid membrane with clotrimazole as the antifungal agent were reported in order to interpret the action basis about the molecularbiology of this drug.Using the injecting method, we prepared three bilayer lipid membranes(BLM) respectively,and by the cyclic voltammetry method we determined properties of BLM before and after adding clotrimazole into the membranes.It was found that clotrimazole could remarkably reduce the membrane resistance and demonstrated that the drug as an antifungal substance might certainly change the permeability of bilayer lipid membrane.

