final dose
4.③Effects of serum containing drug on BEL7402 cells: HCC BEL7402 cells (introduced from Animal Experiment Center of Sun Yet-Sen University) were randomly assigned into 7 groups (10-well in each group): control group (added in RPMI-1640 medium in serum before drug administration with the 100 g/L serum final concentration), 5-FU group prepared with human serum RPMI-1640 medium containing 100 g/L concentration, 0.3, 0.6 and 0.9 mg/L final mass concentration 5-FU (Shanghai Xudong Haipu Pharmaceutical Company, Ltd, number 050106, 10 mL in each) and Chinese drug group (human serum was added with RPMI-1640 medium after taking drugs of 0.83, 1.67 and 2.50 mL/kg dose, 100 g/L serum final concentration).

