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1.Effects of High Glucose, Insulin on Expression of Glucose Transporter 4, Cbl-associated Protein and Changes of Cytoskeleton in Rat Glomerular Mesangial Cells in Vitro
高糖和胰岛素对肾小球系膜细胞GLUT4、CAP表达及细胞骨架的改变收藏指正
2.OBJECTIVE: To investigated the effects of high glucose, insulin on expression of Glucose Transporter 4 (GLUT4), Cbl-associated protein (CAP) and cytoskeleton protein F-actin of glomerular mesangial cells (GMCs) in order to explore the function of Glucose Transporter 4, Cb1-associated protein and F-actin in the genesis and development of diabetic nephropathy (DN).
目的:探讨高糖、胰岛素对肾小球系膜细胞GLUT4和CAP的mRNA表达及细胞骨架蛋白F-actin的影响,进一步研究糖尿病肾病发生发展中GLUT4及其下游分子F-actin和CAP的重要作用。收藏指正
3.Value of ~(18)FDG-PET in the diagnosis of lung cancer and expression and clinical significance of glucose transporter 1 in lung cancer
18FDG-PET在肺癌诊断中的价值和GLUT1在肺癌细胞中的表达及其临床意义的相关研究收藏指正
4.Thus, overexpression of the glucose transporter gene via the introduction of a herpes simplex viral vector into the nervous system protected neurons from focal ischemic injury (64).
这样,葡萄糖载体基因的过度表达通过疱疹单一腺病毒载体进入到神经系统,保护神经元不受局部缺血损伤(64)。收藏指正
5.Two signal transduction pathways of insulin-stimulated glucose transporter 4 translocation were found recently: one is PI3K signaling pathway,the other is Cb1 associated protein(CAP)/Cbl signaling pathway.
目前发现至少有两条胰岛素刺激葡萄糖转运蛋白4易位的信号转导通路:PI3K途径和Cb1相关蛋白(CAP)/Cb l途径。收藏指正
6.AIM:To investigate the effects of tumor necrosis factor-α(TNFα)and pioglitazone on glucose transporter 4(GLUT4)mRNA and protein expression in 3T3-L1 adipocytes,and explore the time dependence.
目的:观察肿瘤坏死因子α和噻唑烷二酮类药物吡格列酮对3T3-L1脂肪细胞中葡萄糖转运子4(glucose transporter4,GLUT4)mRNA和蛋白表达的影响,并了解其是否有时间依赖性。收藏指正
7.Objective To explore the effect of glucose transporter(GLUT) on the course of fetal growth restriction(FGR) and molecular mechanism of Chinese herbal medicine(CHM) on supplementing kidney and Qi, and activating blood circulation in treating FGR.
目的 探讨葡萄糖转运蛋白 (GL UT)的表达在胎儿生长受限 (fetal growth restriction,FGR)发生发展中的作用以及补肾益气活血防治 FGR的分子机制。收藏指正
8.OBJECTIVE:To investigate continuous pressure-induced expression of energy metabolism genes:hypoxia-inducible factor 1α(HIF-1α) ,glucose transporter-1(GLUT-1) and vascular endothelial growth factor(VEGF) in rabbit annulus fibrosus(AF) .
目的:观察持续压力损伤后,兔纤维环内能量代谢相关基因:低氧诱导因子1α、葡萄糖转运蛋白1和血管内皮生长因子的表达情况。收藏指正
9.Using semiquantitative RT-PCR techniques, it was found that TNF-α inhibited glucose transporter 4 (GLUT4) and c-cbl-associated protein (CAP) gene expression. Aspirin did not influence GLUT4 and CAP gene expression, but alleviated the inhibiting effect of TNF-α on GLUT4 and CAP expression.
半定量RT PCR发现 ,TNF α抑制葡萄糖转运体 4(GLUT4)和c cbl相关蛋白 (CAP)基因的表达 ,而阿司匹林并不影响GLUT4和CAP的表达 ,但是能减低TNF α对GLUT4和CAP表达的抑制作用。收藏指正
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