6.Methods Sixty patients with FD confirmed by gastroscopy and pathology were enrolled in this study. Of them, 30 Hp positive (Hp+ ) and 30 Hp negative (Hp-).
8.Conclusion The prevalence of severe GERD in Hp(-) was higher than that in Hp(+). The rate of recurrence in Hp(+) GERD was high after eradicating Hp 12 months. Hp may has protective effect for GERD.