intestinal villus
1.with addition of NE in the reperfusion fluid significantly aggravated the reperfusion injury. Reperfusion with POB although increased SMA blood to 146.5±3.7% of its orginal levels, the animals, however, developed severe reperfusion damage, including intestinal hemorrhage and edema, intestinal villus necrosis etc.
2.Neither methotrexate nor leucovorin was used in control group. Serum ALT and Cr,protein content of the liver,intestinal mucosa ALP and GGT,villus length were detected at 72 h after methotrexate injection.
3.Porcine respiratory coronavirus (PRCV) was first isolated in Belgium in 1984 by Pensaert. It has a selective tropism for respiratory tissue with very little to no replication in the intestinal tissue and with no evidence of villus atrophy or gastroenteritis of infected swine.
4.Results: Compared with sham operation group, the intestinal villi were sloughed in I/R group with decreased villus height and crypt depth(P<0.01), the DAO activities were decreased(P<0.01), and MLN bacterial translocation rates were increased(P<0.05).
5.Supplementation with 2 g/kg MMT also decreased significantly(P<0.05) diarrhea incidence and increased(P<0.05) villus height and the villus height to crypt depth ratio as compared with control. However,supplementation with MMT had no (P>0.05) effect on growth performance,intestinal microflora as compared with control.
