liver sinusoid
1.METHODS: Human liver sinusoid endothelial cells (HLSECs) were mixed respectively with human liver cancer cell line BEL7402, human colon cancer cell line LS174T, and human esophageal cancer cell line NEC, and then inoculated into NOD/SCID mice or BALB/c nude mice. The mice inoculated with only tumor cells were used as controls. Tumor growth was observed.
2.The results revealed that the collagen type Ⅰ and Ⅲ had the same distribution pattern. In normal rat liver, the quantity of PⅢP was significantly less than:that of collagen type Ⅰ and Ⅲ in portal triads(P<0. 01) and more abundant in sinusoid(P<0. 01 , P< 0. 05 respectively). We deduced that in sinusoid,,he leading component was newly synthesized col- lagen , while the mature collagen.
