macrophage-monocyte
1.SUMMARY BACKGROUND DATA: Soluble receptor proteins derived from the macrophage-monocyte lineage potentiate the inflammatory cytokine response early in AP.
2.Results:mRNA expression for MIP-1α(Macrophage inflammatory protein-1α),MCP-1(Monocyte chemoattractant protein-1)and their receptors CCR1/CCR2 were significantly increased in the lungs on day 7 and 14 postinfection.
3.The mechanisms of increased activity of acyl coenzyme A: cholesteryl acyltransferase1 in monocyte/macrophage derived foam cells
4.Study on the cytotoxicity of cord blood monocyte-macrophage activated by IL-2 and TNFα on K562 leukemic cell
5.Regulation of production of IL 10 and IL 12 by IFN γ in HHV 6 infected monocyte/macrophage lineage
6.Immuohistochemistry method was used to measure the activation of NF- κ B, expression of ICAM-1 and monocyte/macrophage(EDl) in rat renal tissue.
7.Ourpurpose of this research was to investigate the influence of pulmonarytype II epithelial cells on the inflammatory process of EPF. In thisresearch, we observed the expression of monocyte chemotactic protein (MCP) -1 mRNA in pulmonary type II epithelial cells stimulated bybleomycin, alveolar macrophage-conditioned media (AMCM) and bleomycintreated alveolar macrophage-conditioned media (BMCM) respectively.
8.The amount of various infiltrating lymphoid cells was also indicated (cell no. high power view) termed reactive T cell index (TCI), pan B cell index (BCI), monocyte/macrophage index (MMI), and dendritic cell index (DCI) respectively.
9.Results Compared with those of the UUO group,the monocyte/macrophage filtration and the expression of MCP-1 and ColⅠwere decreased significantly in the treatment group,and the degree of tubular degeneration and interstitial fibrosis was also ameliorated.
10.The immuno?associated molecules on the BMSCs were assayed by FACS. Results It was found that MHC?Ⅰ,MHC?Ⅱ,VCAM?1 and B7?2 molecules essential to antigen presenting cells were expressed abundantly. F4/80 and NLDC145, the maker molecules of monocyte?macrophage and dendritic cell were also highly expressed on BMSCs.
