4.We introduced nu gene, from PBI/1 nudemouse, to 615/PBI beige mouse with NK cell deficient, and bred T and NK cell combined immunodeficient PBI/2 beige nudemouse. It is proved that this mouse is of T and NK , cell combined immunodeficiency.
9.Objective To evaluate the inhibitory effects of survivin antisense oligodeoxyribonucleotide (ASODN) on human medullary thyroid cancer (MTC) inoculated into the nudemouse.
10.Objective To investigate synergistic effect of bromocriptine (BCT) combining tumor necrosis factor-α (TNF-α) on reversing multidrug resistance in a nudemouse model of liver neoplasm.