phosphorus pentasulfide
1.The optimum preparation technology was conducted by orthogonal design L9(34) with different ratios on yield of product. The initial conditions of synthesizing technology were determined: in acid making, n -butanol and 2-ethyl-hexanol:phosphorus pentasulfide = 4.2∶1 ,the charging temperature was 60 ℃ . reaction temperature was 95 ℃ , reaction time was 1.5 h;
2.The selective thionation of α acetylamino β [4(1,2 dihydro 2 oxoquinoline)]propionic acid and its ester with phosphorus pentasulfide as a thionation reagent yielded the target compound α acetylamino β [4(1,2 dihydro 2 thioquinoline)]propionate. The structure of the new compound was studied by IR、UV、+ 13 C NMR、GC/MS and Element analysis,and substitutional site of thionation of acetylamine was discussed.
