polysorbate
1.Add 2 ~ 8C 1 % polysorbate 1.0ml and mix them again.
2.Conclusion: AmB-PBCA-NP modified by polysorbate 80 can pass the blood-brain barrier.
3.[Result] AmB-PBCA-NP and AmB-PLA/PEG-NP were successfully prepared with polysorbate 80 (T-80) coated as surface modification.
4.Methods: AmB-PBCA-NP was prepared by incubation,with the surface modified by polysorbate 80.High-performance liquid chromatography(HPLC) method was established using acetonitrile and water(40?60,4% of acetic acid) as mobile phase; detection was done at 405 nm.
5.Methods: Uses the ultraviolet-obviously spectrophotometric metho, Polysorbate 80 solution in the 284nm wave length place determination and as increases the solvent take it Zedoary Turmeric Oil and Glucose Injection inoculation fluid absorption.
