potentiate
1.A substance or factor that will not promote cancer by itself but can potentiate cancer when acting with carcinogenic agents.
2.SUMMARY BACKGROUND DATA: Soluble receptor proteins derived from the macrophage-monocyte lineage potentiate the inflammatory cytokine response early in AP.
3.These results suggest that AKOS is an effective immunomodulatory drug which can potentiate the humoral and cellular immune function.
4.Objective: To screen a concentration of Zn2+ which can potentiate 2-arsono-acetic acid(ASAC) induced apoptosis on human hepatocellular carcinoma SMMC-7721 cells, and research the potential mechanism of it.
5.The results showed that TTD could significantly potentiate the toxicities of DNR and HHT in drug-resistant leukemic cell lines (K562/A02,K562/HHT),the IC50 values decreased 15.8 bold and 19.1 fold respectively(P<0.05);
6.Meanwhile , it was found that SOD inhibitor -diethy dithiocarbamate (DDC) could potentiate the effects of microwave irradiation or ultrastructure of S-180 cells , SOD activity (7.8 ± 1.3 vs 11.0 ± 1.2 U/106RBC , P<0.01), and MDA concentration (6.98 ± 0.55 vs 5.64 ± 0.58 mmol, L , P<0.01 )in blood .
7.RESULTS: On mice fed on Rhubarb root, Jianpixiaoshi i Pill can effectively potentiate immunity, improve the velocity of stomach and intestine, expedite the advance speed of ink in the small intestine and the velo city of gastric emptying, reduce the residual rate of methyl orange in stomach.
8.3. Cytotoxity of CDA-Ⅱ is low, and CDA-Ⅱ could strongly potentiate cisplatin-inhbited proliferation of SWO-38 cells. At 0.5 ~ 2 g/Lof CD A- II, IC50 of cisplatin on glioma cell line was reduced from 4.73 mg/L to 2.55 mg/L> 0.60 mg/LN 0.19 mg/L, respectively.
9.University or college shall transit the concept, build the environment, and organize the crew and carry forward the speciality in order to reinforce the macro-organization of educational research; the teachers shall build up confidence to hunt for tasks, to make acquainted with procedures, to master methodology and to potentiate the drilling of educational research.
10.Second, Zn2+ potentiate ASAC induced apoptosis in SMMC-7721 cells and the probablely mechanism of inducing apoptosis is throug the mitochondrial membrane potential loss and the down-regulation of the gene expression of Bcl-2. Third,One of the probablely mechanisms that ASAC induced apoptosis in SMMC-7721 cells is throug the G2/M arrest.
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