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1.Finally, β FNA (100 μmol/L, an M ENK receptor inhibitor) facilitated the inhibitive effect of L NNA on the Glu level, while nor BIN (100 μmol/L, a DYN receptor inhibitor) suppressed that effect.
对L NNA抑制谷氨酸水平二次升高效应 ,10 0 μmol/L的甲硫氨酸脑啡肽受体抑制剂 β funaltrexamine(β FNA)可显著协同 ,而 10 0 μmol/L的强啡肽 B受体抑制剂norbinaltorphimine(nor BIN)则显著逆转。收藏指正
2.Effects of epidermal growth factor receptor tyrosine kinase inhibitor BPI-2009H on cancer cells of tongue
表皮生长因子受体酪氨酸激酶抑制剂BPI-2009H抗肿瘤作用的研究收藏指正
3.NEW YORK (Reuters Health) Dec 20 - Disulfide benzamide (DIBA), an estrogen receptor zinc finger inhibitor, restores sensitiity to tamoxifen in resistant breast cancer cells, both in itro and in mice, researchers report in the December issue of Cancer Cell.
纽约（路透社健康信息）12月20日，在12月份《癌症细胞》的杂志中，研究这宣称，一种雌激素受体锌指抑制物二硫苯甲酰胺(DIBA)，可以使乳癌三苯氧胺（他莫西芬）耐药的癌细胞重新恢复敏感性，在试管试验和老鼠试验中均有这样的结果。收藏指正
4.Objective To investigate the effects of gene transfer of a β-adrenergic receptor(β 2AR) kinase inhibitor (βARKct) on pulmonary β 2-adrenergic receptor and cyclic adenosine monophosphate(cAMP) following β 2AR agonist treatment in asthmaticmice, and to analyze the relationship between the routes of gene delivery and the changes of β 2AR and cAMP.
目的　研究基因转染β肾上腺素能受体激酶抑制剂 (βARKct)对应用 β2 肾上腺素能受体 (β2 AR)激动剂后支气管哮喘 (简称哮喘 )小鼠肺部 β2 AR和环腺苷酸 (cAMP)的作用 ,并探讨不同基因转染途径对两者的影响。收藏指正
5.Urokinase-type plasminogen activator (uPA), its receptor (uPAR) and plasminogen activator inhibitor- 1(PAI-1) are part of the urokinase-type plasminogen activator system, playing an important role in degrading extracellular matrix and dissolution of the basement membrane.
uPA(urokinase-type plasminogen activator，uPA)及其受体(uPA receptor，uPAR)和抑制剂(plasminogen activator inhibitor-1，PAI-1)属于尿激酶型纤溶酶原激活剂系统(uPA system，uPAs)，在降解细胞外基质、溶解基底膜过程中起重要作用。收藏指正
6.Methods ~ 3 H-thymidine incorporation test was used to estimate the UⅡ-induced proliferative potential of AFs from SHR and the influence of Urantide(UⅡ receptor antagonist) and PD98059(ERK1/2 inhibitor).
方法用胸腺嘧啶掺入法(3H-TdR)观察UⅡ诱导的SHR大鼠血管外膜成纤维细胞的增殖活性,及UⅡ受体拮抗剂Urantide、细胞外信号调节激酶1/2(ERK1/2)特异性的抑制剂PD98059对UⅡ诱导SHR大鼠血管外膜成纤维细胞增殖活性的影响;收藏指正
7.The inhibition of F-suc was concentration-dependent and could be blocked by the antagonist of intracellular glucocorticoid receptor RU38486, but not by the protein synthesis inhibitor actidione.
糖皮质激素胞内受体阻断剂RU38486能阻断GC的快速抑制作用。 蛋白质合成抑制剂放线菌酮不能阻断该快速作用。收藏指正
8.In addition, HSC-T6 cells were preincubated for 60 min with U0126, an inhibitor of MAPK/ERK kinase, irbesartan, an AT-1 receptor blocker, N-acetylcysteine (NAC), antioxidant, angiotensin converting enzyme inhibitor (ACEI), or tumor necrosis factor α (TNFα) prior to exposure to AngⅡ or Aldo. Then the protein expression of phospho-P42/44 was measured by Western blotting.
另外,观察AngⅡ1型受体(AT1受体)阻断剂伊贝沙坦(irbesartan),细胞外调节蛋白激酶(ERK)特异性抑制剂U0126,抗氧化剂乙酰半胱氨酸(NAC)、血管紧张素转化酶抑制剂(ACEI)和肿瘤坏死因子α(TNFα)对磷酸化P42/44蛋白水平的影响。收藏指正
9.Interleukin-1 receptor antagonist (IL-lra), a member of IL-1 family, is a naturally occurring IL-1 inhibitor as "receptor antagonist", which blocks IL-1 mediated biological responses.
白细胞介素1受体拮抗剂(IL-1ra)为IL-1家族中的一员,其本身无任何激动剂的作用,但能特异性地与IL-1受体结合,从而拮抗IL-1的各种生物学效应。收藏指正
10.Conclusion The inhibitory effect of angiotensin Ⅱ receptor blockers (ARB) or combined application of ARB with angiotensin coverting enzemy inhibitor (ACEI) on the levels of aldosterone was greater than that of ACEI.
结论血管紧张素Ⅱ受体拮抗剂(ARB)或ARB与血管紧张素转换酶抑制剂(ACEI)合用对醛固酮的抑制作用强于ACEI。收藏指正
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