5.?bstract:Using the method of simulated hypoxia and i.c. v. administration we studied the effect of secondmessenger pathways on CRF secretion under the condition of hypoxia.
6.Moreover, the internal cellular Ca 2+ could act as a secondmessenger to transduct the drought signal, and regulate the physiological responses induced by drought stress.
7.Cyclic adenosine monophosphate (cAMP) is a ubiquitous intracellular secondmessenger. Its level depends on the activity of a variety of enzymes and proteins, which control the synthesis and degradation of cAMP.
8.ObjectivesIn eukaryocyte,Nitric Oxide(NO) has many biological function as a secondmessenger and neurotransmitter,It has wide biology and antivirus effect,participate in many physiological and pathological procession.
9.Phospholipase-gamma1(PLC-γ1)mediate the hydrolysis of phosphatidylinositol4,5-dipho-sphate(PIP2)to the secondmessenger molecules inositol1,4,5-triphosphate(IP3)which increases intracellular levels of free Ca 2+ and diaclglycetol(DAG).
10.Objective To study the role of the changes of secondmessenger protein kinase C (PKC), inositol 1,4,5 trisphosphate (IP 3) and expression of immediately early gene c fos protein (c fos) in the pathogenesis of hypoxic ischemic encephalopathy (HIE) of neonatal rats.
