telomerase-negative
1.Will their rate of attrition when very long be as slow as seen in telomerase-negative mouse cells?
2.Significant difference of SPF was found between telomerase activity positive and negative groups, and between p53 mutation protein positive and negative groups.
3.The expression of telomerase activity does not correlate with SPF in astrocytoma and anaplastic astrocytoma,but in glioblastoma multiforme,SPF in telomerase activity positive samples was markedly higher than that in the negative ones,and statistical analysis reveals that SPF vary noticeably between the positive and negative samples.

