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1.Renin secretion is controlled by at least four mechanisms that are not mutually exclusive: A renal vascular receptor responds to changes in tension in the afferent arteriolar wall; a macula densa receptor detects changes in the delivery rate or concentration of NaCl in the distal tubule; circulating angiotensin has a negative feedback effect on renin secretion; and the sympathetic nervous system stimulates renin secretion via the renal nerve mediated by β receptors.
肾素的分泌至少受四种互不排斥的机制控制：肾血管受体对向心小动脉壁张力变化的反应；致密斑受体发现远端肾小管内氯化钠传递速率或浓度的变化；循环的血管紧张素对肾素的分泌的负反馈效应；和交感神经系统经由β受体介导的肾神经刺激分泌肾素。收藏指正
2.Angiotensin II ( Ang II ) plays crucial role in the pathogenesis of atherosclerosis and hyper-tension, its most cardiovascular effects are mediated by the Ang II type 1 receptor ( AT1 - R) .
AngⅡ在动脉硬化和高血压的发病机制中有重要作用，其大多数心血管作用由血管紧张素Ⅱ1型受体(AT_1-R)介导。收藏指正
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