MRD
2.and evaluate its clinical value in the minimal residual disease(MRD).
4.Objective: Using two kinds of methods to detect minimal residual . disease(MRD)in acute lymphoblastic leukemia approach the clinical significance of MRD.
5.In seven out of 13 cases of persisted MRD and of 1 case of reappearing MRD, the bone marrow relapsed and 5 of them died.
6.Three out of the 9 MRD-positive patients relapsed within 3 to 6 months;
7.Application of PCR in detection of IgH and TCR gene rearrangement in MRD
8.The micro residual disease (MRD) of case 2 and 3 disappeared after DLI.
9.BCR/ABL, ETO gene and the gene rearrangment of IgH as the indication of MRD.
10.Depression of learning and memory behavior happened with the terminal degeneration of the MrD NBM projection.
