cisterna
3.Conclusion Two times injections of arterial blood into cisterna magna is a reliable method for making DCV after SAH in rats.
5.Objective: To evaluate the capability of sodium nitroprusside (SNP) in reversing delayed cerebral vasospasm (DCV) after subarachnoid hemorrhage (SAH), when administered into cisterna magna.
6.Results: The display rate of MRI for fetal craniocerebral main structure was high such as: hemicerebral lobe, cerebellar, brain stem (mesencephals, pons, oblongata), brain ventricle, brain cisterna, etc.
7.The transcerebellar (or suboccipitobregmatic) iew allows examination of the mid-brain and posterior fossa; this iew is used for measurement of the transerse cerebellar diameter (TCD) and cisterna magna (CM).
8.Eighteen dogs were randomly divided into artificial cerebrospinal fluid (ACSF) group, sense group and antisense group. Using the model of craniocerebral explosive injury, ACSF, the sense oligonucleotides to TNF-α and the antisense oligonucleotides to TNF-α were administered into cerebellomedullar cisterna before injury respectively in three groups, and then the intracranial pressure and contents of brain H 2 O in the bilateral hemispheres in three groups were compared.
9.Methods: Eighteen dog s were randomly divided into artificial cerebral spinal fluid (ACSF) group, sens e and antisense group. With the model of explosive injury to craniocerebral we d eveloped, ACSF, the sense oligonucleotide to TNF-α and the antisense oligonucl eotide to TNF-α were administered respectively in 3 groups through preinjectio n into cerebellomedullar cisterna, and the water contents of the brain in the bi lateral hemispheres in the 3 groups were measured.
10.When rats were given pyrimethamine 7 mg/ kg/d x 3(total dose=10.5 x clinical total dose), the foetus skeleton dysmorphosis rate was 69.2% (27/39) and the dilation rate of cisterna fossae lateralis cerebri 29% (9/ 31). Both were significantly higher than those in the group subjected to chloroquine of 140 mg/kg/d x 3(=14 x clinical total dose).
