2.Hirudoid forte and placebo were applied for 10 days. Analgetics and anti-inflammatory agents were not used. Assessment criteria were pain on pressure, oedema anderythema.
4.The results showed that the wheal reaction was inhibited by terfenadine, therefore, the end point dilution(EPD)changed from 10-5.6 to 10-3.9(P<0.01). There was no significant difference of wheal size and EPD in placebo group.
